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| Player | Team | Date | Inn. | Count | Type | Dist. (ft.) | Field | Opponent | Home/Away | Pitcher | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| David Ortiz | Opponent | Jul 24, 2009 | 1 | 1-0 | Three-run | N/A | Center | Boston Red Sox | Away | Jeremy Guthrie | Loss |
| David Ortiz | Opponent | Aug 31, 2007 | 1 | 1-1 | Solo | N/A | Right | Boston Red Sox | Away | Radhames Liz | Win |
| David Ortiz | Opponent | Sep 08, 2007 | 1 | 1-0 | Two-run | 395 | Right-center | Boston Red Sox | Home | Jon Leicester | Win |
| David Ortiz | Opponent | Sep 18, 2013 | 1 | 0-0 | Two-run | N/A | Right | Boston Red Sox | Away | Wei-Yin Chen | Win |
| David Ortiz | Opponent | Apr 23, 2010 | 2 | 2-1 | Solo | N/A | Left-center | Boston Red Sox | Away | Jeremy Guthrie | Loss |
| David Ortiz | Opponent | May 01, 2010 | 2 | 1-0 | Solo | 376 | Right | Boston Red Sox | Home | Brad Bergesen | Win |
| David Ortiz | Opponent | Jul 31, 2009 | 3 | 3-0 | Two-run | N/A | Right-center | Boston Red Sox | Home | Jeremy Guthrie | Loss |
| David Ortiz | Opponent | May 31, 2008 | 3 | 1-1 | Solo | 410 | Center | Boston Red Sox | Home | Garrett Olson | Loss |
| David Ortiz | Opponent | Jul 31, 2007 | 3 | 0-0 | Two-run | N/A | Right | Boston Red Sox | Away | Erik Bedard | Win |
| David Ortiz | Opponent | Sep 09, 2003 | 3 | 2-2 | Two-run | 430 | Right | Boston Red Sox | Home | Damian Moss | Loss |
| David Ortiz | Opponent | Jul 28, 2013 | 3 | 2-0 | Two-run | N/A | Left-center | Boston Red Sox | Home | Jason Hammel | Loss |
| David Ortiz | Opponent | Apr 02, 2014 | 3 | 1-1 | Two-run | N/A | Right | Boston Red Sox | Home | Ubaldo Jimenez | Loss |
| David Ortiz | Opponent | Sep 20, 2004 | 4 | 0-1 | Two-run | N/A | Right | Boston Red Sox | Away | Matt Riley | Win |
| David Ortiz | Opponent | Sep 24, 2003 | 4 | 1-0 | Solo | N/A | Right | Boston Red Sox | Away | Pat Hentgen | Win |
| David Ortiz | Opponent | Sep 04, 2000 | 4 | N/A | Solo | N/A | N/A | Minnesota Twins | Away | Jose Mercedes | Win |
| David Ortiz | Opponent | Sep 22, 2010 | 4 | 1-0 | Three-run | N/A | Right | Boston Red Sox | Away | Kevin Millwood | Loss |
| David Ortiz | Opponent | Jun 13, 2013 | 4 | 1-1 | Solo | N/A | Right-center | Boston Red Sox | Home | Kevin Gausman | Win |
| David Ortiz | Opponent | Apr 19, 2014 | 4 | 3-2 | Solo | N/A | Right | Boston Red Sox | Away | Bud Norris | Loss |
| David Ortiz | Opponent | Sep 06, 2007 | 5 | 3-2 | Solo | 380 | Right | Boston Red Sox | Home | Rocky Cherry | Loss |
| David Ortiz | Opponent | Apr 07, 2004 | 6 | 0-0 | Three-run | 371 | Right | Boston Red Sox | Home | Rick Bauer | Loss |
| David Ortiz | Opponent | Aug 03, 2003 | 6 | 2-2 | Solo | N/A | Left-center | Boston Red Sox | Home | Rick Helling | Loss |
| David Ortiz | Opponent | Aug 06, 2002 | 6 | 0-0 | Two-run | N/A | Right-center | Minnesota Twins | Home | Sidney Ponson | Win |
| David Ortiz | Opponent | Aug 13, 2002 | 6 | 3-1 | Solo | N/A | Right | Minnesota Twins | Away | Scott Erickson | Loss |
| David Ortiz | Opponent | May 21, 2012 | 6 | 3-1 | Solo | 424 | Right | Boston Red Sox | Home | Tommy Hunter | Loss |
| David Ortiz | Opponent | Sep 08, 2009 | 7 | 2-2 | Solo | N/A | Center | Boston Red Sox | Away | Bob McCrory | Loss |
