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| Player | Team | Date | Inn. | Count | Type | Dist. (ft.) | Field | Opponent | Home/Away | Pitcher | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Evan Longoria | Opponent | Apr 06, 2010 | 6 | 2-2 | Solo | 473 | Left | Tampa Bay Rays | Away | Kevin Millwood | Loss |
| Darryl Strawberry | Opponent | Jun 17, 1998 | 1 | 2-1 | Three-run | 465 | Right-center | New York Yankees | Home | Mike Mussina | Loss |
| Pedro Munoz | Opponent | May 25, 1996 | 6 | N/A | Three-run | 463 | Center | Oakland Athletics | Home | David Wells | Loss |
| Jeffrey Hammonds | Orioles | Sep 15, 1997 | 7 | 2-1 | Two-run | 460 | Center | Cleveland Indians | Home | Eric Plunk | Win |
| Mo Vaughn | Opponent | Jul 07, 1996 | 9 | 1-0 | Three-run | 457 | N/A | Boston Red Sox | Home | Randy Myers | Loss |
| Miguel Cabrera | Opponent | Jul 13, 2012 | 5 | 3-1 | Solo | 454 | Center | Detroit Tigers | Home | Luis Ayala | Loss |
| Vladimir Guerrero | Opponent | May 22, 2004 | 5 | 0-0 | Two-run | 453 | Left | Los Angeles Angels | Away | Sidney Ponson | Loss |
| Eric Davis | Opponent | Sep 26, 1993 | 2 | 2-2 | Solo | 452 | N/A | Detroit Tigers | Home | Arthur Rhodes | Loss |
| Albert Belle | Orioles | Jun 29, 1999 | 3 | 2-0 | Solo | 452 | Center | Toronto Blue Jays | Away | Pat Hentgen | Loss |
| Mark Reynolds | Orioles | Aug 07, 2011 | 7 | 0-0 | Solo | 450 | Left-center | Toronto Blue Jays | Home | Ricky Romero | Loss |
| Juan Gonzalez | Opponent | Jul 26, 1992 | 8 | 1-2 | Solo | 450 | Left | Texas Rangers | Home | Mike Mussina | Loss |
| Manny Ramirez | Opponent | Aug 14, 1995 | 4 | N/A | Two-run | 450 | Left-center | Cleveland Indians | Home | Jamie Moyer | Loss |
| Russell Branyan | Opponent | Jun 11, 2009 | 7 | 2-1 | Solo | 450 | Center | Seattle Mariners | Home | Brian Bass | Loss |
| Chris Davis | Orioles | Apr 20, 2013 | 2 | 2-0 | Solo | 448 | Center | Los Angeles Dodgers | Home | Josh Beckett | Win |
| David Segui | Orioles | Aug 19, 2001 | 7 | 1-0 | Solo | 448 | Center | Boston Red Sox | Away | Sun-Woo Kim | Win |
| Miguel Tejada | Orioles | Jul 23, 2005 | 9 | 3-2 | Solo | 448 | Left | Tampa Bay Rays | Away | Danys Baez | Loss |
| Brian Giles | Opponent | Jul 26, 1996 | 1 | N/A | Two-run | 447 | Right-center | Cleveland Indians | Home | Mike Mussina | Loss |
| Mike Piazza | Opponent | Jun 14, 2001 | 6 | 0-0 | Solo | 447 | Left | New York Mets | Home | Josh Towers | Win |
| Jim Thome | Opponent | Jul 06, 2006 | 3 | 3-1 | Grand slam | 447 | Center | Chicago White Sox | Away | Russ Ortiz | Loss |
| Ken Griffey Jr. | Opponent | Aug 15, 1997 | 1 | 2-2 | Two-run | 446 | N/A | Seattle Mariners | Home | Jimmy Key | Loss |
| Chili Davis | Opponent | Jun 10, 1995 | 4 | N/A | Solo | 445 | N/A | Los Angeles Angels | Home | Ben McDonald | Win |
| Vernon Wells | Opponent | Sep 16, 2004 | 3 | 0-0 | Two-run | 445 | Left | Toronto Blue Jays | Away | Rodrigo Lopez | Win |
| Harold Baines | Orioles | Sep 05, 1998 | 5 | 1-0 | Two-run | 445 | Right | Seattle Mariners | Away | Ken Cloude | Loss |
| Adam Jones | Orioles | May 31, 2013 | 3 | 1-0 | Two-run | 444 | Center | Detroit Tigers | Home | Max Scherzer | Win |
| Mark Reynolds | Orioles | Jun 26, 2011 | 4 | 1-2 | Solo | 443 | Left-center | Cincinnati Reds | Home | Homer Bailey | Win |
