| Player | Team | Date | Inn. | Count | Type | Dist. (ft.) | Field | Opponent | Home/Away | Pitcher | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ty Wigginton | Orioles | Apr 16, 2010 | 5 | 0-0 | Two-run | N/A | Left | Oakland Athletics | Away | Dallas Braden | Loss |
| Alex Gonzalez | Opponent | Apr 09, 2010 | 3 | 0-0 | Solo | 409 | Left-center | Toronto Blue Jays | Home | Brad Bergesen | Loss |
| Alex Gonzalez | Opponent | Apr 11, 2010 | 4 | 0-0 | Solo | 403 | Left | Toronto Blue Jays | Home | Kevin Millwood | Loss |
| Carlos Pena | Opponent | Apr 14, 2010 | 1 | 0-0 | Three-run | 408 | Left-center | Tampa Bay Rays | Home | Brad Bergesen | Loss |
| Marco Scutaro | Opponent | Apr 24, 2010 | 7 | 0-0 | Three-run | N/A | Left | Boston Red Sox | Away | Matt Albers | Loss |
| Robinson Cano | Opponent | Apr 28, 2010 | 3 | 0-0 | Solo | 395 | Right-center | New York Yankees | Home | Jeremy Guthrie | Loss |
| Ty Wigginton | Orioles | May 01, 2010 | 6 | 0-0 | Solo | 415 | Left | Boston Red Sox | Home | Tim Wakefield | Win |
| Jonathan Van Every | Opponent | May 01, 2010 | 3 | 0-0 | Solo | 422 | Center | Boston Red Sox | Home | Brad Bergesen | Win |
| David Ortiz | Opponent | May 01, 2010 | 8 | 0-0 | Solo | 401 | Right | Boston Red Sox | Home | Alberto Castillo | Win |
| Jason Varitek | Opponent | May 02, 2010 | 5 | 0-0 | Solo | 402 | Right | Boston Red Sox | Home | Kevin Millwood | Win |
| J.D. Drew | Opponent | May 02, 2010 | 7 | 0-0 | Solo | 398 | Left-center | Boston Red Sox | Home | Kevin Millwood | Win |
| Michael Cuddyer | Opponent | May 08, 2010 | 4 | 0-0 | Solo | 367 | Left | Minnesota Twins | Away | Jeremy Guthrie | Win |
| Luke Scott | Orioles | May 13, 2010 | 8 | 0-0 | Grand slam | 376 | Left-center | Seattle Mariners | Home | Brandon League | Win |
| Mike Sweeney | Opponent | May 13, 2010 | 6 | 0-0 | Solo | 398 | Center | Seattle Mariners | Home | Kevin Millwood | Win |
| Ty Wigginton | Orioles | May 15, 2010 | 2 | 0-0 | Solo | 414 | Left | Cleveland Indians | Home | Mitch Talbot | Loss |
| Russell Branyan | Opponent | May 16, 2010 | 9 | 0-0 | Two-run | 354 | Right | Cleveland Indians | Home | Alberto Castillo | Loss |
| Luke Scott | Orioles | May 18, 2010 | 7 | 0-0 | Solo | 358 | Right | Kansas City Royals | Home | Zack Greinke | Win |
| Corey Patterson | Orioles | May 18, 2010 | 8 | 0-0 | Solo | 390 | Right-center | Kansas City Royals | Home | Blake Wood | Win |
| Adam Jones | Orioles | May 21, 2010 | 2 | 0-0 | Two-run | N/A | Right-center | Washington Nationals | Away | Scott Olsen | Win |
| Josh Willingham | Opponent | May 22, 2010 | 3 | 0-0 | Two-run | N/A | Left-center | Washington Nationals | Away | Brad Bergesen | Loss |
| Aaron Hill | Opponent | May 29, 2010 | 6 | 0-0 | Solo | N/A | Left | Toronto Blue Jays | Away | Chris Tillman | Loss |
| Lyle Overbay | Opponent | May 29, 2010 | 8 | 0-0 | Two-run | N/A | Right-center | Toronto Blue Jays | Away | Alberto Castillo | Loss |
| Jose Bautista | Opponent | May 30, 2010 | 8 | 0-0 | Solo | N/A | Left-center | Toronto Blue Jays | Away | Will Ohman | Loss |
| Kevin Youkilis | Opponent | Jun 05, 2010 | 7 | 0-0 | Solo | N/A | Left | Boston Red Sox | Home | Jeremy Guthrie | Loss |
| Nick Swisher | Opponent | Jun 08, 2010 | 1 | 0-0 | Two-run | N/A | Center | New York Yankees | Home | Kevin Millwood | Loss |
