| Player | Team | Date | Inn. | Count | Type | Dist. (ft.) | Field | Opponent | Home/Away | Pitcher | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ty Wigginton | Orioles | Apr 19, 2010 | 9 | 0-1 | Solo | N/A | Left | Seattle Mariners | Away | Shawn Kelley | Loss |
| Casey Kotchman | Opponent | Apr 19, 2010 | 3 | 1-1 | Two-run | N/A | Right | Seattle Mariners | Away | Brad Bergesen | Loss |
| Adam Jones | Orioles | Apr 23, 2010 | 7 | 3-2 | Two-run | N/A | Left | Boston Red Sox | Away | Daniel Bard | Loss |
| David Ortiz | Opponent | Apr 23, 2010 | 2 | 2-1 | Solo | N/A | Left-center | Boston Red Sox | Away | Jeremy Guthrie | Loss |
| Ty Wigginton | Orioles | Apr 24, 2010 | 6 | 3-2 | Solo | N/A | Left-center | Boston Red Sox | Away | John Lackey | Loss |
| Adam Jones | Orioles | Apr 24, 2010 | 9 | 3-2 | Solo | N/A | Left-center | Boston Red Sox | Away | Ramon Ramirez | Loss |
| Jason Varitek | Opponent | Apr 24, 2010 | 5 | 2-0 | Solo | N/A | Left-center | Boston Red Sox | Away | Brian Matusz | Loss |
| Marco Scutaro | Opponent | Apr 24, 2010 | 7 | 0-0 | Three-run | N/A | Left | Boston Red Sox | Away | Matt Albers | Loss |
| Kevin Youkilis | Opponent | Apr 24, 2010 | 7 | 0-1 | Three-run | N/A | Left | Boston Red Sox | Away | Kam Mickolio | Loss |
| Miguel Tejada | Orioles | Apr 25, 2010 | 7 | 2-0 | Two-run | N/A | Left | Boston Red Sox | Away | Hideki Okajima | Win |
| Jorge Posada | Opponent | Apr 27, 2010 | 4 | 0-1 | Solo | N/A | Right | New York Yankees | Home | Kevin Millwood | Win |
| Nick Markakis | Orioles | Apr 28, 2010 | 7 | 1-0 | Solo | 407 | Left-center | New York Yankees | Home | CC Sabathia | Loss |
| Robinson Cano | Opponent | Apr 28, 2010 | 3 | 0-0 | Solo | 395 | Right-center | New York Yankees | Home | Jeremy Guthrie | Loss |
| Robinson Cano | Opponent | Apr 29, 2010 | 4 | 1-0 | Solo | 399 | Right-center | New York Yankees | Home | Brian Matusz | Loss |
| Robinson Cano | Opponent | Apr 29, 2010 | 8 | 0-1 | Solo | 370 | Right | New York Yankees | Home | Alberto Castillo | Loss |
| Miguel Tejada | Orioles | Apr 30, 2010 | 8 | 1-0 | Solo | 417 | Left | Boston Red Sox | Home | Daniel Bard | Win |
| J.D. Drew | Opponent | Apr 30, 2010 | 2 | 0-1 | Solo | 382 | Left-center | Boston Red Sox | Home | David Hernandez | Win |
| Dustin Pedroia | Opponent | Apr 30, 2010 | 6 | 0-1 | Solo | 361 | Right | Boston Red Sox | Home | David Hernandez | Win |
| J.D. Drew | Opponent | Apr 30, 2010 | 8 | 2-2 | Solo | 402 | Center | Boston Red Sox | Home | Jim Johnson | Win |
| Ty Wigginton | Orioles | May 01, 2010 | 5 | 2-0 | Solo | 368 | Left-center | Boston Red Sox | Home | Daisuke Matsuzaka | Win |
| Matt Wieters | Orioles | May 01, 2010 | 5 | 1-1 | Three-run | 372 | Left-center | Boston Red Sox | Home | Daisuke Matsuzaka | Win |
| Ty Wigginton | Orioles | May 01, 2010 | 6 | 0-0 | Solo | 415 | Left | Boston Red Sox | Home | Tim Wakefield | Win |
| Nick Markakis | Orioles | May 01, 2010 | 6 | 2-1 | Three-run | 345 | Right | Boston Red Sox | Home | Tim Wakefield | Win |
| Luke Scott | Orioles | May 01, 2010 | 7 | 0-1 | Solo | 332 | Right | Boston Red Sox | Home | Tim Wakefield | Win |
| David Ortiz | Opponent | May 01, 2010 | 2 | 1-0 | Solo | 376 | Right | Boston Red Sox | Home | Brad Bergesen | Win |
