| Player | Team | Date | Inn. | Count | Type | Dist. (ft.) | Field | Opponent | Home/Away | Pitcher | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Luke Scott | Orioles | May 13, 2010 | 8 | 0-0 | Grand slam | 376 | Left-center | Seattle Mariners | Home | Brandon League | Win |
| Curtis Granderson | Opponent | Jun 08, 2010 | 3 | 2-2 | Grand slam | N/A | Right | New York Yankees | Home | Kevin Millwood | Loss |
| Corey Patterson | Orioles | Jul 09, 2010 | 9 | 2-2 | Grand slam | N/A | Right | Texas Rangers | Away | Neftali Feliz | Win |
| Yunel Escobar | Opponent | Jul 18, 2010 | 2 | 1-0 | Grand slam | N/A | Left | Toronto Blue Jays | Home | Brian Matusz | Loss |
| Jason Kubel | Opponent | Jul 25, 2010 | 3 | 1-0 | Grand slam | N/A | Right-center | Minnesota Twins | Home | Jake Arrieta | Loss |
| Kelly Shoppach | Opponent | Aug 14, 2010 | 4 | 2-2 | Grand slam | N/A | Left | Tampa Bay Rays | Away | Brian Matusz | Loss |
| Adam Jones | Orioles | Apr 06, 2010 | 3 | 3-2 | Solo | N/A | Right | Tampa Bay Rays | Away | James Shields | Loss |
| Nolan Reimold | Orioles | Apr 08, 2010 | 3 | 1-1 | Solo | N/A | Left | Tampa Bay Rays | Away | Andy Sonnanstine | Win |
| Matt Wieters | Orioles | Apr 06, 2010 | 6 | 3-2 | Solo | N/A | Right | Tampa Bay Rays | Away | James Shields | Loss |
| Luke Scott | Orioles | Apr 06, 2010 | 4 | 2-1 | Solo | N/A | Right-center | Tampa Bay Rays | Away | James Shields | Loss |
| Felix Pie | Orioles | Apr 12, 2010 | 1 | 1-0 | Solo | 392 | Right-center | Tampa Bay Rays | Home | Matt Garza | Loss |
| Ty Wigginton | Orioles | Apr 13, 2010 | 10 | 0-1 | Solo | N/A | Left | Tampa Bay Rays | Home | Rafael Soriano | Loss |
| Miguel Tejada | Orioles | Apr 14, 2010 | 4 | 1-2 | Solo | 402 | Left-center | Tampa Bay Rays | Home | David Price | Loss |
| Ty Wigginton | Orioles | Apr 19, 2010 | 9 | 0-1 | Solo | N/A | Left | Seattle Mariners | Away | Shawn Kelley | Loss |
| Evan Longoria | Opponent | Apr 06, 2010 | 6 | 2-2 | Solo | 473 | Left | Tampa Bay Rays | Away | Kevin Millwood | Loss |
| Evan Longoria | Opponent | Apr 07, 2010 | 8 | 1-0 | Solo | N/A | Left-center | Tampa Bay Rays | Away | Cla Meredith | Loss |
| Alex Gonzalez | Opponent | Apr 09, 2010 | 3 | 0-0 | Solo | 409 | Left-center | Toronto Blue Jays | Home | Brad Bergesen | Loss |
| Alex Gonzalez | Opponent | Apr 11, 2010 | 4 | 0-0 | Solo | 403 | Left | Toronto Blue Jays | Home | Kevin Millwood | Loss |
| Alex Gonzalez | Opponent | Apr 11, 2010 | 8 | 2-2 | Solo | 344 | Left | Toronto Blue Jays | Home | Kevin Millwood | Loss |
| Edwin Encarnacion | Opponent | Apr 11, 2010 | 9 | 3-1 | Solo | 400 | Left | Toronto Blue Jays | Home | Cla Meredith | Loss |
| Reid Brignac | Opponent | Apr 12, 2010 | 3 | 0-2 | Solo | 345 | Right | Tampa Bay Rays | Home | Jeremy Guthrie | Loss |
| Carl Crawford | Opponent | Apr 12, 2010 | 8 | 2-1 | Solo | 402 | Right | Tampa Bay Rays | Home | Mark Hendrickson | Loss |
| B.J. Upton | Opponent | Apr 14, 2010 | 7 | 0-2 | Solo | 395 | Center | Tampa Bay Rays | Home | Jason Berken | Loss |
| Ty Wigginton | Orioles | Apr 24, 2010 | 6 | 3-2 | Solo | N/A | Left-center | Boston Red Sox | Away | John Lackey | Loss |
| Adam Jones | Orioles | Apr 24, 2010 | 9 | 3-2 | Solo | N/A | Left-center | Boston Red Sox | Away | Ramon Ramirez | Loss |
